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Mesothelioma and Asbestos

Asbestos is a naturally occurring mineral that is found in thin, long fibres. Workers who are exposed asbestos regularly are at risk of developing mesothelioma as well as other lung diseases.

It may take decades for symptoms to show up after exposure to asbestos. Different asbestos types may cause different symptoms.

Pleural Mesothelioma

Pleural mesothelioma occurs in the lung's outer lining also known as pleura. It is the most common mesothelioma type, accounting for up 70 to 79% of all diagnosed cases. Patients with this disease suffer from chest pain and breathlessness and may experience the sensation of weight in the chest.

Exposure to asbestos, a family of minerals comprised of microscopic fibers, typically causes this type of cancer. Once inhaled, the fibers stick inside the lungs and cause irritation that leads to scarring and DNA mutations. The pleura is the area that surrounds the lungs and chest cavity This means that these irritations can affect both the lungs as well as the heart of a person. Mesothelioma symptoms typically don't show until 30 to 50 years after exposure.

The most frequent symptoms of pleural mesothelioma include chest pain and breath shortness. Patients may also feel tightness in their chest, coughing or difficulty breathing. People with this cancer often have an history of exposure to asbestos in the workplace. Construction, manufacturing and shipbuilding are the most frequent jobs which put people at risk danger of developing pleural melanoma. People who served in the military are at greater risk due to the extensive use asbestos in Navy vessels and bunkers in the Army.

The most commonly used staging method for pleural mesothelioma is the TNM (tumor lymph nodes, lymph nodes and metastases) staging system. The stage a patient has upon diagnosis will help their doctor determine the most effective treatment plan for them. Patients suffering from pleural mesothelioma who is in stage three or stage four will have a less favorable outlook than those in a lower stage. Mesothelioma in stage four can develop into the liver, heart or diaphragm. This can make it more difficult to treat and increase the risk of complications for patients.

Peritoneal Mesothelioma

Unlike pleural mesothelioma, which develops in the lung lining, peritoneal mesothelioma is found in the peritoneum -- it is a membrane that lines the abdominal cavity and organs like the intestines and the liver. Similar to pleural mesothelioma, exposure to asbestos case is the cause of peritoneal mesothelioma. The disease is much less prevalent than pleural mesothelioma, with just 300-500 cases being diagnosed each year.

As with pleural asbestosis, symptoms can take several years to show. Patients generally suffer from abdominal pain and may also have a lump in their abdomen. This type of mesothelioma may also cause nausea, weight loss and fever. Many of these symptoms could be misinterpreted as digestive issues, leading to a misdiagnosis.

Generally speaking, doctors can detect mesothelioma through an extensive health history and physical examination. Imaging tests like X-rays and CT scans are a way to identify mesothelioma. These tests can reveal tumors and other cancer signs that are not evident on X-rays.

These test results enable doctors to diagnose mesothelioma and determine the stage. They also offer treatment options. The stage is determined by the type of cell as well as whether the cancer has spread.

Asbestos exposure is the main risk factor. People who have worked in professions that involve asbestos, such as plumbing or electrical work, manufacturing or construction, are at a higher risk of developing the disease. Even if someone does not work in one of these areas, he or she can be exposed to asbestos litigation to asbestos through family members and other sources. Anyone who thinks they're at risk should consult a doctor. A mesothelioma specialist can help those who have had a experience with asbestos to understand more about their risk.

Risk Factors

Asbestos is the primary mesothelioma-related risk factor. It accounts for as much as 80percent of cases. Exposure to asbestos can happen through work, military service, or by living with someone who works with asbestos or used to do so. When exposed to asbestos, the particles are able to be inhaled into abdomen and lungs. These particles can cause irritation to the linings and can cause cancerous cells to form in the mesothelium. Following exposure to asbestos mesothelioma is likely to occur between 15 and 60 year.

Other risk factors include smoking, genetics and aging. People in their 40s and 50s are more likely be diagnosed with mesothelioma compared to those who are younger or older. Mesothelioma can take between 20 and 60 years before it manifests cancer symptoms after the first exposure. It is important to remember that mesothelioma can develop in people who were exposed to asbestos lawyer, but did not work with it directly. This is known as secondary or indirect asbestos exposure, and is as dangerous as direct asbestos exposure.

Smoking increases a person's chances of developing mesothelioma since it damages the mesothelium and makes it more vulnerable to asbestos. Mesothelioma can also be aggravated by certain illnesses such as asbestosis and pneumonia. It is also important to note that mesothelioma occurs more frequently in men than women. Men are more likely than women to have been exposed to asbestos for longer periods of time and to work with asbestos for longer periods of time. Men are also more likely to have lived with someone who had been exposed to asbestos, and to have asbestos legal (published on Okna Samara)-containing fibers on their clothing. Women tend to be less in contact with asbestos, and they don't usually bring asbestos home on their clothes.

Diagnosis

It is difficult to identify mesothelioma due to its symptoms being often similar to other diseases. This could lead to patients being wrongly diagnosed.

The first step in identifying mesothelioma is for NYU Langone doctors to perform an examination and write note of the medical history of the patient including asbestos exposure. Doctors may also request an CT scan or chest X-ray in order to look for lumps, abnormalities and evidence of exposure to asbestos. These include plaques on the pleura, pleura that are thickened and calcium deposits.

Other diagnostic tests include a magnetic resonance image or MRI test, which makes use of magnets and radio waves in order to produce a series of precise images of the insides of the body. Another method doctors use to diagnose mesothelioma is through the procedure of a surgical biopsy. When a biopsy is performed doctors will remove a small piece of tissue from pleura or the peritoneum, to be tested further. A pathologist is then able to examine the tissue under a microscope to see if it is contaminated with cancerous cells.

Mesothelioma can be classified based on the mesothelial type involved, whether the cells are benign or malignant, and the location, type, and stage of the tumor. Some types of mesothelioma have an increased risk of spreading or metastasizing, so it's important to get a definitive diagnosis so doctors can treat it before it becomes out-of-control.

Doctors can also perform tests in the lab on tumors to determine specific proteins, genes or other factors that can help them describe the characteristics of cancer and plan treatment. These results are called staging.

Treatment

A diagnosis of mesothelioma may be frightening. It is crucial to remember that cancer can be treated, especially at its early stages. Many mesothelioma patients live for a long time with the disease without it spreading to other organs of their body.

Exposure to asbestos may cause mesothelioma in a number of ways. Asbestos fibres, too small to be felt or observed with the naked eyes can be airborne, causing irritation to the lung's lining (pleura). In time the irritation can lead to the formation of scar tissue, which eventually lead to tumors.

The Pleura is a covering that protects the lungs, heart and abdomen. Mesothelium is made up of cells that react when exposed to asbestos. They cause inflammation of the tissue and cause it to become scarred. Overtime, these changes lead to the development of malignant mesothelioma cancers.

Shortness of breath, chest discomfort or fluid buildup on the lungs are all indications of the pleural mesothelioma. In rare instances, the cancer can spread to the tissues surrounding the heart and reproductive organs.

If imaging scans show an underlying mass in the lungs or stomach, a doctor will order biopsies. The procedure involves the removal of some of the fluid or tumor for lab tests. The results will confirm a mesothelioma diagnosis and indicate the most effective treatment plan.

There are a variety of treatment for mesothelioma such as chemotherapy and surgery. Most doctors use a combination of these treatments. Patients may also benefit from taking part in a clinical trial of new mesothelioma treatments. Patients can learn more by speaking with a mesothelioma doctor who has treated the disease.